Effectiveness Of Pre-Exposure Prophylaxis (PrEP) In Reducing The Transmissions Of HIV Virus In Heterosexual Sero-Discordant Sexual Encounters. A Systematic Literature Review

Please, use these as the paper’s Research Objectives:

i. To determine the efficacy of PrEP in the transmissions of HIV virus among the heterosexual sero-discordant sexual couples.

ii. To measure gender differences in the uptake of Prep.

iii. To measure the safety of PrEP.

8. Please use this as the paper’s Research Question:

i. Is the usage of PrEP effective in reducing HIV transmission amongst individuals of different gender

9) The methodology written is too narrative. Please revise it and follow steps outlined in the attached document [BABA file].

10)There is no explicit inclusion or exclusion criteria, no evidence table showing quality assessment or data abstraction. Add a table showing this evidence and also include an explicit inclusion/exclusion criteria. Please.

11) Add an automated Table of Contents [and also a List of Tables/Figures if need be].

12) Please use this as the aim of the study:

i. The study’s aims to examine the means through which PrEP is used to reduce the transmission of HIV virus among sero-discordant heterosexual couples

13) It was noted that the methods of statistical analysis were not highlighted. Please ensure that you highlight them very clearly so I can see easily

14) It was also noted that that the majority of the papers used were on MSM can you source heterosexual related papers?

15) Please delete the following queries/research objectives (if they still appear in the paper). Just use the ones above:

i.  Is the use of PrEP harmless in humans?

ii.  Does the gender difference affect the outcome of the prep application?

iii. Are the approaches presently employed for PrEP utilization safe to humans? alongside the specific objective section.

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